CHICAGO -- Tuesday's first inning was bad for Roy Oswalt.
The fifth inning was even worse for Ian Kinsler.
And the final score? Well, it was just downright ugly for the Rangers.
Oswalt allowed three first-inning home runs and Kinsler's two-out error in the fifth led to seven runs, as the White Sox whipped the Rangers, 19-2, on Tuesday at U.S. Cellular Field.
"Every center-cut ball we put on that plate they certainly didn't miss," Rangers manager Ron Washington said. "We were thoroughly beat tonight. Just couldn't stop their offense."
Tuesday's offensive outbreak was easily the biggest of the season for the White Sox, who set season highs in runs, hits (21), extra-base hits (10) and margin of victory (17).
All of that added up to the most lopsided loss of the season for the Rangers, who previously endured a 21-8 defeat to the Mariners on May 30.
The majority of the damage came against Oswalt, who gave up a career-high 11 runs, nine of which were earned. Both are the highest run totals allowed by a Rangers pitcher this season.
Oswalt (2-1, 7.79 ERA) gave up 13 hits, tying the career high he allowed in his previous start against Detroit, and also surrendered three home runs in one inning for only the second time in his career, the other coming on April 22, 2009, when he allowed three in the sixth inning against the Dodgers. It was sixth time in Oswalt's career he allowed at least three homers in a single game.
"They hit pitches that were over the plate," Oswalt said. "I knew they were probably going to come out swinging. Last start, I threw a lot of strikes and I figured they'd watch that."
While Oswalt struggled, White Sox left-hander Chris Sale (10-2, 2.19) was once again dominant. The young All-Star allowed only five hits while throwing 7 1/3 innings of one-run ball, striking out four and walking one.
"He pitched. Changed speeds, didn't just stand out there and use his fastball. Changed speeds, used his changeup, threw his breaking ball," Washington said. "We just didn't do much against him. That's why he's 10-2. Pretty good pitcher."
Chicago's Kevin Youkilis, who went 3-for-6 with four RBIs, hit a two-run homer to begin the first-inning fireworks before Adam Dunn and Alex Rios added solo shots.
Youkilis, Dunn and Paul Konerko strung together RBI knocks in the second and, after Oswalt tossed two scoreless innings, Alexei Ramirez drove in another two with a one-out single in the fifth. Oswalt followed by getting Gordon Beckham to pop out in foul territory and appeared to be out of the inning when a routine grounder was hit to the second baseman Kinsler, who muffed the grounder.
And then it all unraveled for Texas.
Yoshinori Tateyama entered for Oswalt and, after an RBI single by Youkilis, intentionally walked Dunn to load the bases. The White Sox then rattled off four straight hits -- highlighted by a three-run homer by A.J. Pierzynski -- as part of a nine-run fifth.
"That was like an explosion went off and it's fun to watch," Sale said. "I'd like to sit here and point out who did what, but through the lineup, looking down it, everyone swung the bat outstanding. To get that kind of run support kind of calms you down and you just go about your business and [outs] kind of take care of themselves."
Oswalt was charged with 11 runs while Tateyama was charged with five, which were scored as earned runs against the right-hander but counted as unearned runs against the team.
"I missed over the plate, they hit it. Threw some quality pitches they took," Oswalt said. "Kind of fault my mechanics a little bit; ball was kind of leaking back a little bit. Third and fourth [innings], found them a little bit. Still wasn't perfect, but OK."
The White Sox added three more in the seventh on a sacrifice fly by Jordan Danks and when Eduardo Escobar and Dayan Viciedo scored on separate wild pitches.
Elvis Andrus drove in the Rangers' lone runs with a two-run double off Brian Omogrosso in the eighth, which extended Andrus' hitting streak to 10 games.
Oswalt, in his third start with Texas, said he felt fine heading into the game and said his stamina and velocity have improved each outing. Washington also said he thought Oswalt had been throwing well, but just ran into a White Sox offense that exploded for a season-best offensive attack.
"Tonight they swung the bat well. You can't make excuses for what they did," Washington said. "We've had nights like that, too. But they swung the bats, gotta give them credit. They hit the ball hard. It wasn't like they were chinking stuff in there."