The White Sox activated first baseman Paul Konerko from the seven-day disabled list on Friday, one of four roster moves the club made prior to its series opener at Kansas City.
Chicago also recalled left-handed pitcher Hector Santiago from Triple-A Charlotte. To clear space on the 25-man roster, the White Sox placed infielder Orlando Hudson and left-hander Leyson Septimo on the 15-day DL.
Konerko leads the White Sox in batting average (.316) and on-base percentage (.388) and is tied for first in OPS (.892). He last played Aug. 7, when he took an elbow to the head from Royals outfielder Jarrod Dyson while covering first base. Konerko was placed on the DL three days later.
Santiago, who was optioned to Charlotte on July 30, has a 3.66 ERA, 43 strikeouts and 21 walks in 39 1/3 relief innings for the White Sox this season.
Hudson, whose DL stint is retroactive to Thursday, has a contusion in the first metatarsal joint in his left foot. He left Wednesday's game at Toronto after fouling a ball off the foot, and is hitting .182 over 36 games with the White Sox.
Septimo, with a 6.00 ERA over 12 appearances, is suffering from left biceps inflammation. His stint is retroactive to Tuesday.
Andrew Simon is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.