| Date | Transaction | |||
| 4/27/01 | Kip Wells: Recalled pitcher Kip Wells from Triple-A Charlotte. | |||
| Sean Lowe: Optioned pitcher Sean Lowe to Triple-A Charlotte. | ||||
| 4/21/01 | Antonio Osuna: Placed Antonio Osuna on the 15-day disabled list, retroactive to April 11, due to inflamation in right shoulder. | |||
| James Baldwin: Activated pitcher James Baldwin from the 15-day disabled list. | ||||
| 4/12/01 | Lorenzo Barcelo: Recalled pitcher Lorenzo Barcelo from Triple-A Nashville. | |||
| Cal Eldred: Placed pitcher Cal Eldred on the 15-day disabled list. | ||||