| Date | Transaction | |||
| 5/21/01 | Ken Vining: Recalled pitcher Ken Vining from Triple-A Charlotte. | |||
| Optioned outfielder Julio Ramirez to Triple-A Charlotte. | ||||
| 5/15/01 | Sean Lowe: Recalled pitcher Sean Lowe from Triple-A Charlotte. | |||
| 5/13/01 | Optioned Gary Glover to Triple-A Charlotte. | |||
| 5/10/01 | Jeff Liefer: Recalled first baseman Jeff Liefer from Triple-A Charlotte. | |||
| Frank Thomas: Placed Frank Thomas on the 15-day disabled list with a tear in his right triceps. | ||||
| 5/1/01 | Jon Garland: Recalled right-handed pitcher Jon Garland from Triple-A Charlotte. | |||
| Jim Parque: Placed pitcher Jim Parque on the 15-day disabled list, retroactive to April 27, with a sore left shoulder. | ||||
